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This creates a challenging paradox for patients with ME/CFS and Long COVID: when mitochondria are damaged and ATP production drops, the cell lacks the energy required to synthesize new glutathione

Future treatment options The study was conducted by researchers at the University of Gothenburg in collaboration with colleagues at the Medical University of South Carolina

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Cysteine alkylating agent iodo-APAP ( N -(4-hydroxyphenyl)-2-iodoacetamide) was synthesized in-house as previously described (LeBlanc et al., Escherichia coli cells were from laboratory stocks