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Simple fixes help most people: smaller, lower-fat meals, easing up on sulfur-rich foods, staying hydrated, and not lying down right after eating

Estradiol has important effects on the female reproductive organs, including breasts, uterus, and also the endometrium during the regulation of the menstrual cycle, as well as in non-reproductive tissues, such as skeletal, cardiovascular and nervous system

Management includes adequate hydration, over-the-counter analgesia such as paracetamol or ibuprofen, and lifestyle modifications including regular meal patterns

doi: Vaughan RW, Cork RC, Hollander D

Protocol arms now need feeding, fasting, meal response, body composition, and calorimetry endpoints