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Al-Aly thinks that might be an underestimate because even though the study followed huge numbers of people, it covered only about four years, so they might have seen more Alzheimers cases if the study had gone on for longer, which might have translated to a larger benefit

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Clinical trials show superior weight loss outcomes compared to tirzepatide alone, though the combination significantly increases gastrointestinal side effects like nausea and vomiting

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