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After sorting by constitutive 2D and 3D classifications, 3D consensus density maps were reconstructed with global resolutions of 2.5 (without ECD) or 3.3 (with ECD) for compound 2 alone, 2.5 for compound 2 plus GLP-1, and 2.9 for compound 2 plus LY3502970, respectively (Supplementary Fig

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