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"Finding new and better treatments is critically important to help people live healthier lives." References Nirupam M Srinivasan, Mehdi Farokhnia, Lisa A Farinelli, Anna Ferrulli, Lorenzo Leggio, GLP-1 Therapeutics and Their Emerging Role in Alcohol and Substance Use Disorders: An Endocrinology Primer, Journal of the Endocrine Society , Volume 9, Issue 11, November 2025, bvaf141,

Because pediatric patients were never included in most clinical trials for these drugs, plaintiffs argue that prescribing them off-label created unacceptable dangers

More recently, Sears et al

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Many people see improvement as weight stabilizes, calorie intake becomes more consistent, and routines normalizeoften within 6 to 12 months