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A number of dosage protocols appear in the epithalamin and epithalon studies and trials performed to date, the most notable of which has been the Khavinson protocol (or, Russian protocol) for anti-aging and longevity [1]

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The pro-depressant effects of MetSR may be mediated through chronic low-grade inflammation, as evidenced by recent research showing significant mediation (30.8% combined effect) through inflammatory markers including platelets, lymphocytes, neutrophils, C-reactive protein (CRP), leukocytes, and INFLA scores (Qiu et al