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For instance, Zhou et al
While the percentage of the total cell GSH content found in mitochondria is minor (1015%), the mitochondrial glutathione (mGSH) concentration is similar to that found in the cytosol
Toxicol Lett 208:149161 Wu H, Zhang G (2017) Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice
A complicating factor in clinical trials has been the significant inter-individual variability in susceptibility to APAP toxicity 14
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