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Volume I: Report to the General Assembly, Scientific Annexes A and B

Initial or high doses of prebiotics may initially aggravate some patients symptoms, with some bloating and flatulence: introduction should be gradual and monitored

Campbell A, Heydarian R, Ochoa C, Dwivedi AK, Nahleh ZA

Individuals with certain health conditions, such as Lebers disease (a hereditary eye disease), should avoid B12 injections, as they can exacerbate symptoms

Stratifying patients by these markers, as well as by the glial-derived protein S100B (a marker of BBB dysfunction), can predict which patients are most likely to benefit from biological therapies or psychobiotics (Ning et al., 2023