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In a study of healthy adult subjects with mild knee soreness, bromelain supplementation resulted in significant improvement with both 200-mg and 400-mg daily use

This is the first step toward developing that knowledge, which will require large-scale, carefully controlled clinical trials." Rasgon is a member of the Stanford Neurosciences Institute

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When used for weight management, the evidence increasingly supports long-term or indefinite treatment for patients who respond well and tolerate the medication particularly those with obesity-related cardiovascular risk factors