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Once a peptide denatures, it loses its ability to bind to the GLP-1 receptors in your brain and gut

One small case study published last year found that six people who screened positive for alcohol use disorder saw a clinically significant decrease in symptoms while using semaglutide, the active ingredient in Ozempic and another medication, Wegovy, for weight loss

About 12% of Americans have taken one of these popular medications for weight loss, according to a 2025 report by RAND, a nonprofit research organization

For details on how GLP-1 medications work and clinical data, see Independent Wellnesss overview: What Is GLP-1

That excludes, however, government beneficiaries