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For dispensations outside the benefit, both obesity (71.1%) and obesity without a T2DM diagnosis (68.1%) dominated overall and showed an increase of 31% and 76%, respectively, among incident GLP-1 RA patients between 2019 and 2023

Humans express two VMAT encoding genes, SLC18A1 which encodes VMAT1 and SLC18A2 which encodes VMAT2

10.1186/s13098-022-00823-y 134 ZhangJ.ZhangW.YangL.ZhaoW.LiuZ.WangE.et al (2023a)

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A 2013 review in Aging Cell showed that declining systemic IGF-1 correlates with reduced dermal collagen density and skin elasticity in adults over 60