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It was FDA-approved as Geref Diagnostic for evaluating pituitary GH secretory capacity

PLoS ONE 7:e40881 Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, DeBalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Bajpeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL (2012) Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

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A clinician may adjust the dose, slow titration, review meal size, discuss hydration or consider another treatment

A happy gut means more GLP-1 and that means more metabolic wins