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Regulatory Disclaimer on Peptides: Many of the peptides referenced in this article (including BPC-157, TB-500, Ipamorelin, and MOTS-c) are not FDA- approved for the treatment of any medical condition

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By coupling agonism at the GLP-1 receptor with simultaneous agonism at the GIP receptor, a related incretin whose physiological role had been the subject of decades of competing theories, Eli Lilly produced a molecule whose efficacy in trial conditions exceeded semaglutide by a margin too large to dismiss as noise or trial-design artifact