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The mechanism through which these medications may influence OSA is indirect: they reduce body weight, and body-weight reduction reduces upper-airway collapsibility during sleep

That step matters because subtle, time-dependent degradation is difficult to detect by eye

[27] A gene expressed in glial cells actively transports glutamate into the extracellular space, [27] while, in the nucleus accumbens-stimulating group II metabotropic glutamate receptors, this gene was found to reduce extracellular glutamate levels

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