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By activating both GIP and GLP-1 receptors, tirzepatide enhances insulin secretion in a glucose-dependent manner, meaning insulin is released primarily when blood glucose levels are elevated

But it's understandable to want to enjoy cookies, chocolate, and other sweets once in a while as part of an overall balanced, healthy diet

Dennis Bruemmer (Cardiologist and Director of the Center for Cardiometabolic Health in the section of Preventive Cardiology at the Cleveland Clinic)

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The pattern in patient reviews: those reporting substantial weight loss (10+ pounds in 4 weeks) invariably mention concurrent dietary changes, increased exercise, or use of other medications (metformin, GLP-1 agonists)