hold glp 1 before surgery ASA Advises No Longer Holding GLP-1 Agents Prior to for Most Patients GLP-1 Before Surgery: Safety Guidelines

Some evidence suggests these medications may also improve quality of life and psychological wellbeing in patients distressed by weight regain

A smaller appetite doesn't help either

In a post-hoc subgroup analysis of JUPITER subjects (rosuvastatin=725, placebo=680) with a hsCRP 2 mg/L and no other traditional risk factors (smoking, BP 140/90 or taking antihypertensives, low HDL-C) other than age, after adjustment for high HDL-C, there was no significant treatment benefit with rosuvastatin treatment

Curr Pharm Des 2014;20:1121-1125

-glutaredoxin upregulated the expression of the Nrf2 pathway and its downstream enzymes (CAT, SOD), enhanced endogenous antioxidant defence, increased GSH levels and reduced ROS accumulation [125]