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Body mass index (BMI) at baseline, metabolic health status, and duration of obesity can all affect response to therapy

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At this time, there is no other medication like GLP-1s that consistently produces the degree of sustainable, clinically meaningful weight loss while improving metabolic markers, says Dr

GLP-1 medications can be used with other diabetes medicines, but there are special risks to consider: When GLP-1 medications are combined with insulin or medicines called sulfonylureas or meglitinides (which also lower blood sugar), the risk of low blood sugar (hypoglycemia) is higher

McFarlane, S