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3,211 Known side effects of letrozole include digestive upset, low energy, hot flashes, headache, and back pain

Compounded semaglutide is a custom-made version of these medications that are mixed and prepared by compounding pharmacies rather than being mass-produced by pharmaceutical manufacturers

Clinical trials have shown similar weight loss results between the oral pill and injectables

None has posted results to ClinicalTrials.gov as of July 2026

Most patients titrate after 4 weeks, but only if: Side effects are stable Appetite isnt overly suppressed Weight loss is plateaued AND safe to increase Never increase early