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Oral metabolic franchise, a broader portfolio of oral small molecule candidates targeting metabolic disease beyond the lead GLP-1 program Recent Highlights: In May 2026, Structure reported positive end-of-Phase 2 feedback from the FDA for aleniglipron, clearing the way to begin a Phase 3 registrational program for chronic weight management in Q3 2026

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The FDA considers allulose generally recognized as safe (GRAS) with an intake below 0.5 to 0.6 grams per kilogram of body weight per day

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GLP-1 drugs reduce appetite dramatically