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While they are associated with oligodendrocyte maturation and formation of the myelin sheath ( Figure 1 While oligodendrocytes are the main cell type involved in myelination, it is important to stress that both microglia and astrocytes regulate the production and renewal of myelin

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It should also be noted that RBCs lack other NADPH-producing enzymes, and any loss of NADPH cannot be compensated by other pathways