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Extracellular vesicles from endothelial progenitor cells reverse dexamethasone-induced GSH dyssynthesis and changes in several markers of oxidative damage, preventing glucocorticoid-induced osteoporosis in mice by inhibiting ferroptosis of osteoblasts
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Semaglutide and tirzepatide trials demonstrate 5-22% body weight reduction in sedentary or minimally active participants, though individual results vary based on metabolic factors, adherence, and baseline health status
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