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Severe or persistent nausea and vomiting that prevents adequate food or fluid intake, as this may lead to dehydration and acute kidney injurycontact your GP urgently or call NHS 111 for advice Signs of hyperglycaemia including excessive thirst, frequent urination, blurred vision, or unexplained fatigueparticularly relevant as corticosteroids can precipitate or worsen diabetes Symptoms of hypoglycaemia (if also taking diabetes medications) such as trembling, sweating, confusion, or rapid heartbeat Visual changes or severe headaches seek prompt assessment, especially if you have diabetes or are at risk of glaucoma Mood changes or psychological symptoms , as corticosteroids can affect mental health Signs of infection , as corticosteroids suppress immune function Before starting Wegovy whilst on corticosteroid therapy, patients should inform their healthcare provider about: All current medications, including over-the-counter preparations and supplements Any history of pancreatitis, thyroid disease, or diabetic retinopathy Previous adverse reactions to GLP-1 receptor agonists Plans for surgery or medical procedures Regular follow-up appointments are essential for patients taking both medications to monitor treatment response, adjust doses as needed, and address any emerging concerns

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According to the American Diabetes Association, Ozempic (semaglutide) injection is a once-weekly medication in the GLP-1 receptor agonist class of drugs

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Smaller, evenly spaced meals often work better than large, infrequent ones, especially during dose escalation

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