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Animal studies have shown accelerated healing of tendons, ligaments, and intestinal tissue, with proposed mechanisms involving growth hormone receptor signaling, nitric oxide pathways, and angiogenesis (the formation of new blood vessels)

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The neurological symptoms can be particularly concerning

undertook a double blind RCT in which a population with degenerative orthopaedic alteration with neural compression were randomised to a treatment arm of either nucleosides and B12 combination of cytidine monophosphate disodium (CMP) 2.5 mg, uridine triphosphate trisodium (UTP) 1.5 mg and hydroxocobalamin 1000 g orally ( n = 200) or a B12 only regimen of hydroxocobalamin 1.0 mg orally ( n = 200)