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In cancers, highly overexpressed arginase is classically associated with an immunosuppressive phenotype by depleting arginine and inhibiting T cell proliferation, activation, and cytotoxicity, leading to impaired immune function, cancer development, and immune evasion [176,177,178]

Regular breast self-examination from young adulthood onwards, clinical breast examination once every 13 years for women aged 2039 years, and annual mammographic screening from ages 4050 and beyond may increase detection rates (323)

It is a naturally occurring amino acid compound already present in the body

Mediators Inflamm 2019:1082497

It discusses challenges such as low bioavailability and highlights advanced drug delivery systems designed to improve efficacy