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Among the drugs facing loss of exclusivity: Mercks Keytruda, a cancer immunotherapy with over $29 billion in 2024 sales, facing loss of exclusivity in 2028

5 Links between ferroptosis and ophthalmology Ferroptosis, a lipid peroxidation-mediated, iron-dependent form of programmed cell death, has swiftly become a leading focus in ophthalmic disease research in just a few years, as it plays important roles in cataracts, glaucoma, DED, corneal injury, and thyroid-associated ophthalmopathy (TAO), among others

Our results show good concordance with Sanger sequencing of the NS5B region, the reference method, for genotype determination, 1a/1b subtyping and genotype 4, 5 and 6 subtyping, in keeping with recently presented results 26

Doses beyond this point do not proportionally increase GH release but do escalate cortisol and prolactin co-secretion