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PROTAC-based approaches have been developed to selectively degrade aggregation-prone proteins, including QC-01-C175 for tau in AD, XL01126 for LRRK2 in PD, and GW5074 for mutant huntingtin in HD

Between uses, the vial septum should be protected from contamination, and proper aseptic technique should be used for each withdrawal

What this page can do is give you the surrounding context what the injection is, how it acts, the general ranges reported in the literature, and the genetic terrain underneath it all so your clinical conversation starts from a more informed place

L., Olsen, J., Carle, A