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van der Velde AE, Brufau G, Groen AK

Oxidation of phospholipids and proteins in lipoproteins and their role in atherosclerosis Overview The response to retention hypothesis for the initiation of atherosclerosis posits that retention of LDL in the artery wall leads to its modification into highly atherogenic particles that initiate inflammatory responses

J Steroid Biochem Mol Biol 178:8288

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In particular, exosomes derived from HEK293 cells treated with interferon- (INF-) carry a higher amount of OCTN2 with respect to exosomes derived from untreated cells