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Rats heal differently, metabolize compounds differently, and are studied under controlled conditions that dont reflect the complexity of human biology, health history, or dosing

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Cells Vero African green monkey kidney cells were cultured at 37C in a 5% CO2 atmosphere in Eagles Minimum Essential Medium (MEM, HyClone) containing 1.2 mg/ml NaHCO3 and supplemented with 6% (v/v) foetal bovine serum, 2 mM glutamine, 100 IU/ml penicillin and 100 g/ml streptomycin