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Vorinostat: 0.52 M), a PARP inhibitor, and the demethylating agent Decitabine

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and activation of synaptogenic intracellular signaling, including mammalian target of rapamycin complex (TORC1) (Romeo et al., 2015)

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In severe cases, neuropsychiatric symptoms can progress to include visual disturbances (which may reflect optic neuropathy), personality changes, or even psychosis, though these are less common