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10.1016/j.cell.2016.06.028 103 ObermoserG.SontheimerR

A 2025 patent and literature review catalogued ongoing investigations into Src-caveolin-1 and focal adhesion kinase pathway involvement in tissue migration responses (PMID 40005999)

Regulatory agencies, including the US Food and Drug Administration, the European Medicines Agency, and the Pharmaceuticals and Medical Devices Agency, require extensive Phase III clinical trials, immunogenicity assessments, and comprehensive Chemistry, Manufacturing, and Controls data before approving new GLP-1 therapies or label expansions

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We performed this study to confirm the existence of GLP-1R in PTC tissue and the clinical meaning of GLP-1R expression in PTC