The second enzyme, L-aromatic amino acid decarboxylase (AADC a.k.a
Curr Psychiatr Rep 2001;3:101-8
Recent research also suggests semaglutide GLP-1 may have additional benefits, such as reducing the risk of major cardiovascular events in those with type 2 diabetes and high cardiovascular riska promising finding for many of our patients
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however, no significant changes were observed in LDL or total cholesterol.28 A 2022 meta-analysis focusing on adults with metabolic syndrome risk factors reached similar conclusions, noting modest reductions in LDL cholesterol and systolic blood pressure but overall marginal changes in total cholesterol.29 A broader 2024 review summarizing human and preclinical data suggests that astaxanthin may enhance insulin sensitivity and glucose uptake while supporting lipid metabolism and antioxidant balance, though these findings are based on limited trials and changes in biomarkers.30 These effects are thought to involve activation of Nrf2, a cellular pathway that turns on the bodys own antioxidant defenses, and improved mitochondrial energy metabolism, which may help regulate oxidative stress