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It significantly upregulates VEGF (vascular endothelial growth factor) expression, stimulating endothelial cell proliferation and tubule formation

5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase, an enzyme highly expressed in adipose tissue that regulates NAD+ metabolism and cellular energy balance

This effect has been linked to enhanced microvascular development, which increases perfusion and nutrient availability within damaged muscle fibers