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In neuronal senescence model studies, the active ingredient of the product can cross the blood-brain barrier (and act directly on neurons in vitro), increase NAD+ levels in nerve cells, protect mitochondrial function, reduce neuronal apoptosis, and promote the synthesis and release of neurotransmitters (such as dopamine and acetylcholine), thereby improving signal transduction in nerve cells

Evidence-Base Disclosure The published evidence base for AOD-9604 consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments

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