PLP serves as a coenzyme in over one hndred enzymatic reactions, playing a crucial role in amino acid metabolism, neurotransmitter synthesis, gluconeogenesis, and lipid and carbohydrate metabolism
Antacid drugs that neutralize stomach acid, as well as acid-suppressing agents such as proton-pump inhibitors, can inhibit the absorption of vitamin B 12 by preventing its release from food in the stomach
In addition, we observed an upregulation of 1030-fold for SCD, LIPIN1, and DGAT2 genes in low B12 primary Sc adipocytes derived from subjects with overweight and an increase of 20-fold for DGAT2 from subjects with morbid obesity (Fig
When should Neo-B12 Injection not be used
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