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Key Research Findings: In early studies, Retatrutide has demonstrated significant body weight reduction, in part due to increased thermogenesis and lipolysis (Abouelmagd & Abdelrehim

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Clonidine is a centrally acting -adrenergic and imidazoline (I) receptor agonist that reduces central sympathetic outflow and norepinephrine release, resulting in decreased heart rate and peripheral vascular resistance