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The mechanism appears to involve interaction with the endogenous opioid systemDSIP modulates enkephalin and beta-endorphin release, suggesting opioid-system cross-talk

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Neurexins participated in regulating synaptic plasticity Changes in synaptic plasticity are key downstream events in sustained antidepressant effect, and understanding their mechanisms is important for resolving sustained antidepressant effect

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In one study 11 , up to 90% of patients experienced improvements in their skin reactions and other symptoms after undergoing desensitization