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[6] Supplementation with L-carnitine showed improvements on the Clinical Global Impression Scale (CGIS) and other clinical variables

The reported side effects of LC (especially at high doses) include agitation, headaches, diarrhea, nausea, vomiting, anorexia and abdominal discomfort, mostly of mild or moderate severity [95]

10.7554/eLife.12813 Elife 158 StokerT

Thirdly, optimal doses and frequencies of consumption for maximizing the health benefits of hormetic substances remain largely undefined

Users and observers alike reported overwhelmingly positive experiences, citing improvements in self-esteem (77%), social confidence (75%), and physical health (69%)