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Researchers at several institutions outside Zagreb have begun independent replication studies

Hisatomi H, Ohyashiki K, Ohyashiki JH, Nagao K, Kanamaru T, Hirata H, et al

Notably, METTL3 undergoes lactylation, which is essential for capturing target RNA, ultimately reinforcing the immunosuppressive functions of TIMs in CRC via the H3K18la-METTL3/m6A/JAK1/STAT3 signaling pathway

RNA was reverse transcribed using Moloney murine leukemia virus reverse transcriptase (Ambion- ThermoFisher Scientific) and a mixture of anchored oligo-dT and random decamers (Integrated DNA Technologies)

Inhibition of glycolysis prevents behavioural changes in mice with MK801-induced SCZ model by alleviating lactate accumulation and lactylation