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When you lose weight quickly, some of that loss can come from muscle

Cost: Qsymia: around $200 for 30 capsules without insurance Contrave: around $600 for 120 tablets without insurance *Terms and restrictions may apply for certain doses of the pill

In real-world practice, patients who experience severe gastrointestinal side effects may adjust their behavior more freely, drinking more fluids, reducing doses, or taking breaks

Cancer Metab (2020) 8(1):11

In a long-term randomized, double-blind, placebo-controlled study among sufferers of cerebrovascular accidents at high risk of depression, daily supplementation with 2 mg of folic acid, 25 mg of vitamin B6, and 500 g vitamin B 12 significantly lowered the risk of major depressive episodes during a seven-year follow-up period compared to placebo (111)