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[11] Oral health issues, dental problems, and infections (including COVID-19) can also cause taste changes and should be considered as alternative explanations

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More serious deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

Moreover, arhalofenate acid activates AMPK downstream targets to participate in the regulation of mitochondrial function and maintain the function of mitochondrial crest (McWherter et al., 2018)