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In the chronic administration paradigm, animals received two different treatment regimens: a cycle of 4 to 6 injections of cisplatin at 3 mg/kg given over the course of 3 weeks (once every 4 days), followed by a 5-day recovery or a cycle of 2 injections of cisplatin at 5 mg/kg given at a 4 day interval, followed by a 5-day recovery

In addition, there are some genetic variations (mutations) that can increase the chance of developing Parkinsons, but people who have these mutations do not always develop this disease

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Mcmillan KJ, Murray TK, Bengoa-Vergniory N et al (2017) Loss of MicroRNA-7 regulation leads to -synuclein accumulation and dopaminergic neuronal loss in vivo