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Abstract In the SELECT cardiovascular outcomes trial, semaglutide showed a 20% reduction in major adverse cardiovascular events in 17,604 adults with preexisting cardiovascular disease, overweight or obesity, without diabetes

Exact dosages will vary for each individual

During this period, most individuals notice reduced appetite, increased fullness after meals and smaller portion intake

The most common side effects are gastrointestinal: nausea (affecting roughly 20-30% of users at higher doses), diarrhea, vomiting, constipation, and decreased appetite

It works by mimicking the effects of the hormone GLP-1, which helps to increase insulin secretion, reduce glucagon secretion, and slow gastric emptying, thereby improving blood sugar control and promoting weight loss