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Dempsey et Katja Aschenbrenner, Utility of glucagon-like-peptide-1-receptor agonists in mast cell activation syndrome , The American Journal of the Medical Sciences , vol
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When these receptors activate in blood vessels and the autonomic nervous system, they can promote vasodilation (widening of blood vessels), which naturally lowers pressure
A patient with low GLP1R activity may achieve better results with tirzepatide (which recruits the GIP axis) than semaglutide alone