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PMID: 6145137

This high level of basal activity may serve as a signaling set point to counterbalance the inhibitory input from leptin and insulin in appetite regulation 12

Under the assumption that both SGLT2i and GLP-1RA delay mortality of people with type 2 diabetes [41], this should not have a significant effect on the estimation of kidney outcomes

Because digoxin toxicity can present as nausea and vomiting, symptoms that overlap with GLP-1 RA side effects, maintain a low threshold for checking levels in any patient reporting new or worsening GI symptoms after a GLP-1 RA dose increase