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Tesamorelin, a stabilized analog of growth hormone-releasing hormone (GHRH), and Ipamorelin, a highly selective ghrelin mimetic, work in tandem to explore the "dual-pathway" stimulation of the pituitary gland

However, by the time a person enters their 40s, this has slowed to 45 days, and continues to slow as they age

98 KoikeH.IshidaA.HayashiT.ShimamuraM.MizunoS.NakamuraT.et al (2009)

Weeks 3 to 6: Improved energy and recovery from workouts

The main reported benefits are deeper sleep, faster recovery, improved body composition (lean mass up, visceral fat down), better skin tone, and steady energy over 8 to 12 weeks