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Manage expectations: Waiting for weight loss or improved blood sugar control can be stress-inducing

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Further differences between Wegovy and Mounjaro are highlighted in the table: The difference between Wegovy and Ozempic is what the medication is approved for

For complete information about what happens after stopping, including weight regain patterns and timeline, see our detailed guide on how long semaglutide stays in your system

Mounjaro and Ozempic work by binding to and activating these GLP-1 and GIP receptors in the body, which can help regulate blood sugar and promote weight loss by: Improving insulin sensitivity