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That bleeding advantage disappears when strong dual inhibitors of CYP3A4 and P-gp (ketoconazole, ritonavir, clarithromycin) are co-administered, as apixaban exposure can increase by up to 100% [1]

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Lipid peroxidation is a well-characterized effect of ROS that results in damage to the cell membrane as well as to the membranes of cellular organelles (Rathore et al

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