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For patients with hypothyroidism, hyperthyroidism, or those taking levothyroxine, many clinicians choose to monitor TSH and thyroid hormones more closely during the first months of GLP-1 therapy and as weight changes

Visceral signs such as fetal hydrops, hepatosplenomegaly, and cholestatic jaundice in early forms usually preceed neurological and psychiatric manifestations

GLP-1//GIP HM15211

Figure 5 3.5 Overall analysis A total of 60,081 randomized participants were included in the data of these 8 GLP-1RA cardiovascular outcomes trials