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Key areas of scientific investigation include: The role of GLP-1 signaling in modulating dopamine release and reward sensitivity Potential effects on motivation, reinforcement, and impulse-driven behavior Overlap between neural pathways involved in appetite regulation and substance use Much of the early evidence comes from preclinical animal studies
We have very, very few studies here, says Dr
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Summary Patients with type 2 diabetes and cardiovascular disease should be started on either a GLP-1RA, SGLT-i, or both in high-risk cases, while simultaneously tapering any prescribed insulin regimen
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