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Reviews Immunol
3.1.2 Safety In total, 21 TEAEs were reported in 11 participants: 14 events were reported in eight participants (57.1%) with normal renal function, two in one participant (14.3%) with mild renal impairment, and five in two participants (28.6%) with moderate renal impairment (Table 3)
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doi: 10.1007/s11695-023-06484-8 58 FlintARabenABlundellJAstrupA
Felger and Miller, 2012)
That said, its also true that even with both medication and lifestyle changes, there will come a point for any one where they cannot happily eat less and they cannot happily exercise more and their weight living with that life, regardless of where it might fall on a BMI chart, is their best weight, and these medications ongoing use and prescription should not be contingent on achieving a particular BMI (though many insurers do require sustaining a 5% weight loss in order to maintain coverage for a medication)
